The Innate Lymphoid Cell conference in the heart of Berlin | Edina Szabo

The 2nd EMBO Conference on Innate Lymphoid Cells was held in Berlin, Germany at the end of November, 2016. To support the European scientific communities the European Molecular Biology Organisation (EMBO) holds conferences and conference series that cover different and evolving aspects of important subject areas. The conference was held in a historic building in the heart of the city, called Kalkscheune (Limestone barn). The place was already set for Christmas, and had a great feeling about it.

The first day of the conference started with registration in the afternoon, followed by two intensive full days, and closing with the Gala dinner. Dan Littman from the NYU School of Medicine, New York, gave the keynote lecture, and well introduced the topic with his talk entitled “Role of ILCs in integrating host responses to microbiota”. The keynote lecture was followed by a session on “ILC development and activation” with speakers from the US, Netherlands, from the Institut Pasteur in Paris, and McGill University in Montreal.

The second day started early at 8.30 am with talks on “Regulation of ILC fate and functions”, and continued with “ILCs homeostasis” in the afternoon. I have particularly enjoyed the talk by David Withers from the University of Birmingham. His group is looking at the importance of a particular receptor for cytokine production by ILC3 cells in the small intestine. Another talk that caught my attention during the afternoon session was the “ILCs and immune regulation at barrier surfaces” presented by David Artis from Cornell University, New York. His findings showed that commensal microbes have a significant regulatory influence on lymphocyte, innate lymphoid cell, and granulocyte function. After the talks we had a chance to explore the city a little bit in the evening, and try the local cuisine.

The final day started early as well, and by then most of us were pretty exhausted, but we had great talks and the gala dinner to look forward to. Emily Thornton’s talk from University of Oxford, was very interesting, which was exploring how ILC3s are involved in the initiation of acute intestinal inflammation. In the afternoon also several talks were on intestinal ILCs, including speaker such as Henrique Veiga-Fernandes from Lisboa, Arthur Mortha from New York, and David Voehringer from Germany. My favourite talk of the day and the whole conference was the “Innate lymphoid cells and IL-22: functional analysis in zebrafish” by Pedro Pablo Hernandez, whose project is to investigate the existence of ILCs and the conservation of the function of IL-22, which is produced by ILC3 cells.

The highlight of the day was the Gala dinner in the Natural History Museum, right by the dinosaur exhibition.

I would like to take the opportunity to thank NSERC CREATE HPI for funding to attend this conference. I had a great time at the conference, and learnt a lot about ILCs, as well as I had a chance to visit some of my family in Berlin.



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